Name | beta-boswellic acid |
Synonyms | Boswellic acid B-BOSWELLIC ACID BOSWELLIC ACID, B- beta-boswellic acid BETA-BOSWELLIC ACID BOSWELLIC ACID, a-(P) (3a,4)-3-Hydroxyurs-12-en-23-oic Acid (3A,4B)-3-HYDROXYURS-12-EN-23-OIC ACID (3alpha)-3-hydroxyurs-12-en-24-oic acid Urs-12-en-23-oic acid, 3-hydroxy-, (3alpha,4beta)- Beta-BoswellicAcidforU.Lingner-HoffmannCHEMOSGmbHsales (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picene-4-carboxylic acid |
CAS | 631-69-6 |
InChI | InChI=1/C30H48O3/c1-18-10-13-26(3)16-17-28(5)20(24(26)19(18)2)8-9-21-27(4)14-12-23(31)30(7,25(32)33)22(27)11-15-29(21,28)6/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21-,22-,23-,24+,26-,27-,28-,29-,30-/m1/s1 |
InChIKey | NBGQZFQREPIKMG-AKOQEMLPSA-N |
Molecular Formula | C30H48O3 |
Molar Mass | 456.71 |
Density | 1.09±0.1 g/cm3(Predicted) |
Melting Point | 130-135°C |
Boling Point | 556.0±50.0 °C(Predicted) |
Specific Rotation(α) | D +107° (c = 0.75 in CHCl3) |
Flash Point | 304.1°C |
Solubility | Soluble in DMSO |
Vapor Presure | 1.11E-14mmHg at 25°C |
Appearance | White cryst. |
Color | Off-White |
pKa | 4.50±0.70(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.555 |
MDL | MFCD04039448 |
Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from frankincense. |
WGK Germany | 3 |
Plant Source: | frankincense |
Use | β-mastic acid is a major component of mastic (frankincense). A specific, non-redox, 5-lipoxygenase inhibitor for the treatment of inflammation. for content determination/identification/pharmacological experiments. |
biological activity | β-bosulic acid was isolated from the gum grease of bosullia serrate. Β-bosulic acid is a non-reducing inhibitor of 5-lipoxygenase (5-LO) product formation that interacts directly with 5-LO or blocks its translocation. Β-bosulic acid inhibits DNA,RNA and protein synthesis in human leukemia HL-60 cells. |